No — biologic therapy is an add-on treatment, not a replacement for inhaled therapy. Most patients continue their ICS-LABA controller inhaler alongside biologic therapy. However, for patients on oral corticosteroids, a supervised, gradual OCS taper is initiated once biologic response is established — typically after 3–4 months. The goal is OCS-free control, not inhaler discontinuation. Dr. Dixit Kumar Thakur manages all OCS tapering carefully at Pulmovista to avoid adrenal insufficiency.